Structure of PDB 2o68 Chain A Binding Site BS02

Receptor Information
>2o68 Chain A (length=307) Species: 727 (Haemophilus influenzae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DITVYNGQHKEAATAVAKAFEQETGIKVTLNSGKSEQLAGQLKEEGDKTP
ADVFYTELTATFADLSEAGLLAPISEQTIQQTAQKGVPLAPKKDWIALSG
RSRVVVYDHTKLSEKDMEKSVLDYATPKWKGKIGYVSTSGAFLEQVVALS
KMKGDKVALNWLKGLKENGKLYAKNSVALQAVENGEVPAALINNYYWYNL
AKEKGVENLKSRLYFVRHQDPGALVSYSGAAVLKASKNQAEAQKFVDFLA
SKKGQEALVAARAEYPLRADVVSPFNLEPYEKLEAPVVSATTAQDKEHAI
KLIEEAG
Ligand information
Ligand IDPO4
InChIInChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
InChIKeyNBIIXXVUZAFLBC-UHFFFAOYSA-K
SMILES
SoftwareSMILES
CACTVS 3.341[O-][P]([O-])([O-])=O
ACDLabs 10.04[O-]P([O-])([O-])=O
OpenEye OEToolkits 1.5.0[O-]P(=O)([O-])[O-]
FormulaO4 P
NamePHOSPHATE ION
ChEMBL
DrugBankDB14523
ZINC
PDB chain2o68 Chain A Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2o68 The role of the synergistic phosphate anion in iron transport by the periplasmic iron-binding protein from Haemophilus influenzae.
Resolution1.7 Å
Binding residue
(original residue number in PDB)		S139 G140 A141 N175 N193
Binding residue
(residue number reindexed from 1)		S139 G140 A141 N175 N193
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
Biological Process
GO:0006826 iron ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0042597 periplasmic space

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2o68, PDBe:2o68, PDBj:2o68
PDBsum2o68
PubMed17147516
UniProtP35755|FBPA_HAEIN Iron-utilization periplasmic protein (Gene Name=fbpA)

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