Structure of PDB 2myb Chain A Binding Site BS02

Receptor Information

>2myb Chain A (length=153) Species: 9755 (Physeter catodon) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

VLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKFDRFKHLK
TEAEMKASEDLKKHGVTVLTALGAILKKKGHHEAELKPLAQSHATKHKIP
IKYLEFISEAIIHVLHSRHPGDFGADAQGAMNKALELFRKDIAAKYKELG
YQG

Ligand information

Ligand ID

MNC

InChI

InChI=1S/C2H3N/c1-3-2/h1H3

InChIKey

ZRKSVHFXTRFQFL-UHFFFAOYSA-N

SMILES

Software	SMILES
	isocyanide
CACTVS 3.341 OpenEye OEToolkits 1.5.0	C[N+]#[C-]

Formula

C2 H3 N

Name

METHYL ISOCYANIDE

PDB chain

2myb Chain A Residue 155 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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PDB	2myb Structure of Myoglobin-Ethyl Isocyanide: Histidine as a Swinging Door for Ligand Entry
Resolution	1.9 Å
Binding residue (original residue number in PDB)	F43 H64 V68
Binding residue (residue number reindexed from 1)	F43 H64 V68
Annotation score	1

Enzymatic activity

Enzyme Commision number

1.11.1.-
1.7.-.-

Gene Ontology

	Molecular Function
GO:0004601	peroxidase activity
GO:0005344	oxygen carrier activity
GO:0016491	oxidoreductase activity
GO:0019825	oxygen binding
GO:0020037	heme binding
GO:0046872	metal ion binding
GO:0098809	nitrite reductase activity

	Biological Process
GO:0015671	oxygen transport
GO:0019430	removal of superoxide radicals

	Cellular Component
GO:0005737	cytoplasm
GO:0016528	sarcoplasm
GO:0070062	extracellular exosome

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External links

PDB	RCSB:2myb, PDBe:2myb, PDBj:2myb
PDBsum	2myb
PubMed
UniProt	P02185\|MYG_PHYMC Myoglobin (Gene Name=MB)

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