Structure of PDB 2ms1 Chain A Binding Site BS02

Receptor Information
>2ms1 Chain A (length=55) Species: 11786 (Murine leukemia virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ATVVSGQKQDRQGGERRRSQLDRDQCAYCKEKGHWAKDCPKKPRGPRGPR
PQTSL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2ms1 Chain A Residue 101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2ms1 A structure-based mechanism for tRNA and retroviral RNA remodelling during primer annealing.
ResolutionN/A
Binding residue
(original residue number in PDB)		C26 H34 C39
Binding residue
(residue number reindexed from 1)		C26 H34 C39
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:2ms1, PDBe:2ms1, PDBj:2ms1
PDBsum2ms1
PubMed25209668
UniProtP03355|POL_MLVMS Gag-Pol polyprotein (Gene Name=gag-pol)

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