Structure of PDB 2miq Chain A Binding Site BS02

Receptor Information

>2miq Chain A (length=94) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SHMSGGSPLATGTTANTRGASQKKGGEPPALIVDPLMKYICHICNRGDVE
ESMLLCDGCDDSYHTFCLLPPLTSIPKGEWLCPRCVVEEVSKPQ

Ligand information

InChI=1S/Zn/q+2

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Zn

Name

ZINC ION

PDB chain

2miq Chain A Residue 102 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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PDB	2miq Solution NMR Structure of PHD Type 1 Zinc Finger Domain 1 from Lysine-specific Demethylase Lid from Drosophila melanogaster, Northeast Structural Genomics Consortium (NESG) Target FR824J
Resolution	N/A
Binding residue (original residue number in PDB)	G58 C59 C85
Binding residue (residue number reindexed from 1)	G58 C59 C85
Annotation score	1

Enzymatic activity

Enzyme Commision number

1.14.11.67: [histone H3]-trimethyl-L-lysine(4) demethylase.

External links

PDB	RCSB:2miq, PDBe:2miq, PDBj:2miq
PDBsum	2miq
PubMed
UniProt	Q9VMJ7\|KDM5_DROME Lysine-specific demethylase 5 (Gene Name=Kdm5)

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