Structure of PDB 2mfe Chain A Binding Site BS02

Receptor Information
>2mfe Chain A (length=59) Species: 294 (Pseudomonas fluorescens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLILTRKVGESINIGDDITITILGVSGQQVRIGINAPKDVAVHREEIYQR
IQAGLTAPD
Ligand information
>2mfe Chain D (length=22) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gggccaucaaggacgauggucc
<<<<<<<<......>>>>>>>>
Receptor-Ligand Complex Structure
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PDB2mfe Molecular basis for the wide range of affinity found in Csr/Rsm protein-RNA recognition.
ResolutionN/A
Binding residue
(original residue number in PDB)		L23 G27 Q28 Q29 R31 A36 P37 K38 V42 H43 R44 I47 R50 I51 P58
Binding residue
(residue number reindexed from 1)		L23 G27 Q28 Q29 R31 A36 P37 K38 V42 H43 R44 I47 R50 I51 P58
Binding affinityPDBbind-CN: Kd=0.185uM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0048027 mRNA 5'-UTR binding
Biological Process
GO:0006109 regulation of carbohydrate metabolic process
GO:0006402 mRNA catabolic process
GO:0006417 regulation of translation
GO:0045947 negative regulation of translational initiation
GO:0045948 positive regulation of translational initiation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Biological Process
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Cellular Component
External links
PDB RCSB:2mfe, PDBe:2mfe, PDBj:2mfe
PDBsum2mfe
PubMed24561806
UniProtP0DPC3|CSRA1_PSEPH Translational regulator CsrA1 (Gene Name=csrA1)

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