Structure of PDB 2mfc Chain A Binding Site BS02

Receptor Information
>2mfc Chain A (length=59) Species: 294 (Pseudomonas fluorescens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLILTRKVGESINIGDDITITILGVSGQQVRIGINAPKDVAVHREEIYQR
IQAGLTAPD
Ligand information
>2mfc Chain D (length=22) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gggugucgacggauagacaccc
<<<<<<<........>>>>>>>
Receptor-Ligand Complex Structure
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PDB2mfc Molecular basis for the wide range of affinity found in Csr/Rsm protein-RNA recognition.
ResolutionN/A
Binding residue
(original residue number in PDB)		L23 G27 Q29 R31 A36 P37 K38 V40 V42 H43 R44 I47 R50 I51
Binding residue
(residue number reindexed from 1)		L23 G27 Q29 R31 A36 P37 K38 V40 V42 H43 R44 I47 R50 I51
Binding affinityPDBbind-CN: Kd=1.9uM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0048027 mRNA 5'-UTR binding
Biological Process
GO:0006109 regulation of carbohydrate metabolic process
GO:0006402 mRNA catabolic process
GO:0006417 regulation of translation
GO:0045947 negative regulation of translational initiation
GO:0045948 positive regulation of translational initiation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2mfc, PDBe:2mfc, PDBj:2mfc
PDBsum2mfc
PubMed24561806
UniProtP0DPC3|CSRA1_PSEPH Translational regulator CsrA1 (Gene Name=csrA1)

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