Structure of PDB 2m13 Chain A Binding Site BS02

Receptor Information
>2m13 Chain A (length=65) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPVQIDPYLEDSLCHICSSQPGPFFCRDQVCFKYFCRSCWHWRHSMEGLR
HHSPLMRNQKNRDSS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2m13 Chain A Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2m13 The C-Terminal Region of Cytoplasmic Polyadenylation Element Binding Protein Is a ZZ Domain with Potential for Protein-Protein Interactions.
ResolutionN/A
Binding residue
(original residue number in PDB)		C527 C532 H545 H553
Binding residue
(residue number reindexed from 1)		C26 C31 H44 H52
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003730 mRNA 3'-UTR binding
GO:0045182 translation regulator activity
Biological Process
GO:0006417 regulation of translation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2m13, PDBe:2m13, PDBj:2m13
PDBsum2m13
PubMed23500490
UniProtQ9BZB8|CPEB1_HUMAN Cytoplasmic polyadenylation element-binding protein 1 (Gene Name=CPEB1)

[Back to BioLiP]