Structure of PDB 2lmv Chain A Binding Site BS02

Receptor Information
>2lmv Chain A (length=147) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SELTEEQIAEFKDAFVQFDKEGTGKIATRELGTLMRTLGQNPTEAELQDL
IAEAENNNNGQLNFTEFCGIMAKQMRETDTEEEMREAFKIFDRDGDGFIS
PAELRFVMINLGEKVTDEEIDEMIREADFDGDGMINYEEFVWMISQK
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2lmv Chain A Residue 150 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2lmv Structure of androcam supports specialized interactions with myosin VI.
ResolutionN/A
Binding residue
(original residue number in PDB)
D129 D131 D133 M135 E140
Binding residue
(residue number reindexed from 1)
D128 D130 D132 M134 E139
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0030234 enzyme regulator activity
GO:0046872 metal ion binding
GO:0070855 myosin VI head/neck binding
Biological Process
GO:0030048 actin filament-based movement
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0031476 myosin VI complex
GO:0070865 investment cone

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:2lmv, PDBe:2lmv, PDBj:2lmv
PDBsum2lmv
PubMed22851764
UniProtP49258|CALL_DROME Calmodulin-related protein 97A (Gene Name=Acam)

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