Structure of PDB 2lgp Chain A Binding Site BS02

Receptor Information
>2lgp Chain A (length=94) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSPVLTCGPASFQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQ
GDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVAT
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2lgp Chain A Residue 216 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2lgp The Structure, Dynamics, and Binding of the LA45 Module Pair of the Low-Density Lipoprotein Receptor Suggest an Important Role for LA4 in Ligand Release.
ResolutionN/A
Binding residue
(original residue number in PDB)		W193 D196 G198 P199 D200 D206 E207
Binding residue
(residue number reindexed from 1)		W73 D76 G78 P79 D80 D86 E87
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2lgp, PDBe:2lgp, PDBj:2lgp
PDBsum2lgp
PubMed22091758
UniProtP01130|LDLR_HUMAN Low-density lipoprotein receptor (Gene Name=LDLR)

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