Structure of PDB 2ko0 Chain A Binding Site BS02
Receptor Information
>2ko0 Chain A (length=87) Species:
9606
(Homo sapiens) [
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MVQSCSAYGCKNRYDKDKPVSFHKFPLTRPSLCKEWEAAVRRKNFKPTKY
SSICSEHFTPDSFKRESNNKLLKENAVPTIFLELVPR
Ligand information
>2ko0 Chain C (length=16) [
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cgctgcccacacaagc
Receptor-Ligand Complex Structure
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PDB
2ko0
Structural determinants of specific DNA-recognition by the THAP zinc finger
Resolution
N/A
Binding residue
(original residue number in PDB)
Q3 K11 F45 K46 P47 T48 Y50 S51 K70
Binding residue
(residue number reindexed from 1)
Q3 K11 F45 K46 P47 T48 Y50 S51 K70
Binding affinity
PDBbind-CN
: Kd=480nM
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0043565
sequence-specific DNA binding
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Molecular Function
External links
PDB
RCSB:2ko0
,
PDBe:2ko0
,
PDBj:2ko0
PDBsum
2ko0
PubMed
20144952
UniProt
Q9NVV9
|THAP1_HUMAN THAP domain-containing protein 1 (Gene Name=THAP1)
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