Structure of PDB 2ju0 Chain A Binding Site BS02

Receptor Information

>2ju0 Chain A (length=175) Species: 4932 (Saccharomyces cerevisiae)

AKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIY
KQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLS
WAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKI
FKLMDKNEDGYITLDEFREGSKVDP

Ligand information

• Ligand ID: CA
• InChI: InChI=1S/Ca/q+2
• InChIKey: BHPQYMZQTOCNFJ-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Ca++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Ca+2]
• Formula: Ca
• Name: CALCIUM ION
• DrugBank: DB14577
• PDB chain: 2ju0 Chain A Residue 501

Receptor-Ligand Complex Structure

Structure summary

• PDB: 2ju0 Structural insights into activation of phosphatidylinositol 4-kinase (Pik1) by yeast frequenin (Frq1).
• Resolution: N/A
• Binding residue (original residue number in PDB): D109 N111 D113 Y115 I116 T117 E120
• Binding residue (residue number reindexed from 1): D107 N109 D111 Y113 I114 T115 E118
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0005509 calcium ion binding
• GO:0005515 protein binding
• GO:0008047 enzyme activator activity
• GO:0046872 metal ion binding

Biological Process

• GO:0009966 regulation of signal transduction

Cellular Component

• GO:0000139 Golgi membrane
• GO:0005829 cytosol
• GO:0005886 plasma membrane
• GO:0016020 membrane
• GO:0033101 cellular bud membrane
• GO:0043231 intracellular membrane-bounded organelle

External links

• PDB: RCSB:2ju0, PDBe:2ju0, PDBj:2ju0
• PDBsum: 2ju0
• PubMed: 17720810
• UniProt: Q06389|NCS1_YEAST Calcium-binding protein NCS-1 (Gene Name=FRQ1)