Structure of PDB 2j5z Chain A Binding Site BS02

Receptor Information
>2j5z Chain A (length=214) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CQEGPRNCRELLSQGATLSGWYHLCLPEGRALPVFCDMDTEGGGWLVFQR
RQDGSVDFFRSWSSYRAGFGNQESEFWLGNENLHQLTLQGNWELRVELED
FNGNRTFAHYATFRLLGEVDHYQLALGKFSEGTAGDSLSLHSGRPFTTYD
ADHDSSNSNCAVIVHGAWWYASCYRSNLNGRYAVSEAAAHKYGIDWASGR
GVGHPYRRVRMMLR
Ligand information
Ligand IDGAL
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3+,4+,5-,6-/m1/s1
InChIKeyWQZGKKKJIJFFOK-FPRJBGLDSA-N
SMILES
SoftwareSMILES
CACTVS 3.370OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O
OpenEye OEToolkits 1.7.2C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.370OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
ACDLabs 12.01OC1C(O)C(OC(O)C1O)CO
OpenEye OEToolkits 1.7.2C([C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)O)O)O)O)O
FormulaC6 H12 O6
Namebeta-D-galactopyranose;
beta-D-galactose;
D-galactose;
galactose
ChEMBLCHEMBL300520
DrugBank
ZINCZINC000002597049
PDB chain2j5z Chain A Residue 1278 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2j5z Structural Insights Into the Innate Immune Recognition Specificities of L- and H-Ficolins.
Resolution1.73 Å
Binding residue
(original residue number in PDB)		S234 C235 Y236 Y254 V264
Binding residue
(residue number reindexed from 1)		S172 C173 Y174 Y192 V202
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2j5z, PDBe:2j5z, PDBj:2j5z
PDBsum2j5z
PubMed17215869
UniProtO75636|FCN3_HUMAN Ficolin-3 (Gene Name=FCN3)

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