Structure of PDB 2id8 Chain A Binding Site BS02

Receptor Information
>2id8 Chain A (length=279) Species: 37998 (Parengyodontium album) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AAQTNAPWGLARISSTSPGTSTYYYDESAGQGSCVYVIDTGIEASHPEFE
GRAQMVKTYYYSSRDGNGHGTHCAGTVGSRTYGVAKKTQLFGVKVLDDNG
SGQYSTIIAGMDFVASDKNNRNCPKGVVASLSLGGGYSSSVNSAAARLQS
SGVMVAVAAGNNNADARNYSPASEPSVCTVGASDRYDRRSSFSNYGSVLD
IFGPGTDILSTWIGGSTRSISGTSMATPHVAGLAAYLMTLGKTTAASACR
YIADTANKGDLSNIPFGTVNLLAYNNYQA
Ligand information
Ligand ID2DB
InChIInChI=1S/C3H10BO6/c5-1-3(6)2-10-4(7,8)9/h3,5-9H,1-2H2/q-1/t3-/m0/s1
InChIKeyKLKDDPLTQSQDLA-VKHMYHEASA-N
SMILES
SoftwareSMILES
CACTVS 3.341OC[C@H](O)CO[B-](O)(O)O
ACDLabs 10.04O[B-](O)(O)OCC(O)CO
CACTVS 3.341OC[CH](O)CO[B-](O)(O)O
OpenEye OEToolkits 1.5.0[B-](O)(O)(O)OCC(CO)O
OpenEye OEToolkits 1.5.0[B-](O)(O)(O)OC[C@H](CO)O
FormulaC3 H10 B O6
Name(S)-(2,3-DIHYDROXYPROPOXY)TRIHYDROXYBORATE
ChEMBL
DrugBank
ZINCZINC000196075144
PDB chain2id8 Chain A Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2id8 What can be done with a good crystal and an accurate beamline?
Resolution1.27 Å
Binding residue
(original residue number in PDB)		H69 L133 G134 G160 N161 S224
Binding residue
(residue number reindexed from 1)		H69 L133 G134 G160 N161 S224
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) D39 H69 N161 S224
Catalytic site (residue number reindexed from 1) D39 H69 N161 S224
Enzyme Commision number 3.4.21.64: peptidase K.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:2id8, PDBe:2id8, PDBj:2id8
PDBsum2id8
PubMed17139083
UniProtP06873|PRTK_PARAQ Proteinase K (Gene Name=PROK)

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