Structure of PDB 2i0m Chain A Binding Site BS02

Receptor Information

>2i0m Chain A (length=207) Species: 170187 (Streptococcus pneumoniae TIGR4) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

QFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAELIINKDHAIN
QGQSAIELTCARLLALPQVSDLRFVISIMSSCSDLERMGDHMAGIAKAVL
QLKENQLAEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQ
YYYALSKEIIGLMKDQESIPNGTQYLYIIGHLERFADYIANICERLVYLE
TGELVDL

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

2i0m Chain A Residue 219 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	2i0m Crystal structure of the phosphate transport system regulatory protein PhoU from Streptococcus pneumoniae
Resolution	2.4 Å
Binding residue (original residue number in PDB)	E91 D95
Binding residue (residue number reindexed from 1)	E86 D90
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0042803	protein homodimerization activity

	Biological Process
GO:0006817	phosphate ion transport
GO:0030643	intracellular phosphate ion homeostasis
GO:0045936	negative regulation of phosphate metabolic process
GO:2000186	negative regulation of phosphate transmembrane transport

	Cellular Component
GO:0005737	cytoplasm

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Molecular Function

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Cellular Component

External links

PDB	RCSB:2i0m, PDBe:2i0m, PDBj:2i0m
PDBsum	2i0m
PubMed
UniProt	P0A3Y7\|PHOU_STRPN Phosphate-specific transport system accessory protein PhoU homolog (Gene Name=phoU)

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