Structure of PDB 2hvq Chain A Binding Site BS02

Receptor Information
>2hvq Chain A (length=317) Species: 10665 (Tequatrovirus T4) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMFKKYSSLENHYNSKFIEKLYSLGLTGGEWVAREKIHGTNFSLIIERDK
VTCAKRTGPILPAEDFFGYEIILKNYADSIKAVQDIMETSAVVSYQVFGE
FAGPGIQKNVDYGDKDFYVFDIIVTTESGDVTYVDDYMMESFCNTFKFKM
APLLGRGKFEELIKLPNDLDSVVQDYNFTVDHAGLVDANKCVWNAEAKGE
VFTAEGYVLKPCYPSWLRNGNRVAIKCKNSKFSEKKVELSEADNKLVGIL
ACYVTLNRVNNVISKIGPKDFGKVMGLTVQDILEETSREGITLTQADNPS
LIKKELVKMVQDVLRPA
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain2hvq Chain A Residue 336 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2hvq RNA Ligase Structures Reveal the Basis for RNA Specificity and Conformational Changes that Drive Ligation Forward.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		I162 L164 N166 Y206
Binding residue
(residue number reindexed from 1)		I163 L165 N167 Y207
Annotation score4
Enzymatic activity
Enzyme Commision number 6.5.1.3: RNA ligase (ATP).
Gene Ontology
Molecular Function
GO:0003972 RNA ligase (ATP) activity
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0042245 RNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:2hvq, PDBe:2hvq, PDBj:2hvq
PDBsum2hvq
PubMed17018278
UniProtP32277|RLIG2_BPT4 RNA ligase 2 (Gene Name=Y10A)

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