Structure of PDB 2h1k Chain A Binding Site BS02

Receptor Information
>2h1k Chain A (length=58) Species: 10036 (Mesocricetus auratus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNR
RMKWKKEE
Ligand information
Receptor-Ligand Complex Structure
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PDB2h1k Structural basis for induced fit mechanisms in DNA recognition by the pdx1 homeodomain
Resolution2.42 Å
Binding residue
(original residue number in PDB)		R3 R5 T6 Y8 I47 N51 K55
Binding residue
(residue number reindexed from 1)		R1 R3 T4 Y6 I45 N49 K53
Binding affinityPDBbind-CN: Kd=1.2nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:2h1k, PDBe:2h1k, PDBj:2h1k
PDBsum2h1k
PubMed17315980
UniProtP70118|PDX1_MESAU Pancreas/duodenum homeobox protein 1 (Gene Name=PDX1)

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