Structure of PDB 2h1c Chain A Binding Site BS02

Receptor Information
>2h1c Chain A (length=139) Species: 485 (Neisseria gonorrhoeae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MILLDTNVISEPLRPQPNERVVAWLDSLILEDVYLSAITVAELRLGVALL
LNGKKKNVLHERLEQSILPLFAGRILPFDEPVAAIYAQIRSYAKTHGKEI
AAADGYIAATAKQHSLTVATRDTGSFFAADVAVFNPWHL
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain2h1c Chain A Residue 203 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2h1c Structure of FitAB from Neisseria gonorrhoeae bound to DNA reveals a tetramer of toxin-antitoxin heterodimers containing pin domains and ribbon-helix-helix motifs.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		L3 L4 L35 S36 T39
Binding residue
(residue number reindexed from 1)		L3 L4 L35 S36 T39
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0004518 nuclease activity
GO:0004540 RNA nuclease activity
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0044001 migration in host

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Molecular Function
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Biological Process
External links
PDB RCSB:2h1c, PDBe:2h1c, PDBj:2h1c
PDBsum2h1c
PubMed16982615
UniProtQ5F882|FITB_NEIG1 Toxin FitB (Gene Name=fitB)

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