Structure of PDB 2g1p Chain A Binding Site BS02

Receptor Information
>2g1p Chain A (length=244) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KNRAFLKWAGGKYPLLDDIKRHLPKGECLVEPFVGAGSVFLNTDFSRYIL
ADINSDLISLYNIVKMRTDEYVQAARELFVPETNCAEVYYQFREEFNKSQ
DPFRRAVLFLYLNRYGYNGLCRYNLRGEFNVPFGRYKKPYFPEAELYHFA
EKAQNAFFYCESYADSMARADDSSVVYCDPPYAPLNSFTLEQQAHLAEIA
EGLVERHIPVLISNHDTMLTREWYQRAKLHVVKKVDELLALYKP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2g1p Structure and substrate recognition of the Escherichia coli DNA adenine methyltransferase.
Resolution1.89 Å
Binding residue
(original residue number in PDB)		R95 Y119 R124 N126 L127 N132 P134 R137
Binding residue
(residue number reindexed from 1)		R93 Y117 R122 N124 L125 N130 P132 R135
Enzymatic activity
Enzyme Commision number 2.1.1.72: site-specific DNA-methyltransferase (adenine-specific).
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0009007 site-specific DNA-methyltransferase (adenine-specific) activity
GO:0043565 sequence-specific DNA binding
GO:1904047 S-adenosyl-L-methionine binding
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006298 mismatch repair
GO:0009307 DNA restriction-modification system
GO:0009411 response to UV
GO:0032259 methylation
GO:1902328 bacterial-type DNA replication initiation

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Molecular Function
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Biological Process
External links
PDB RCSB:2g1p, PDBe:2g1p, PDBj:2g1p
PDBsum2g1p
PubMed16524590
UniProtP0AEE8|DMA_ECOLI DNA adenine methylase (Gene Name=dam)

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