Structure of PDB 2fl3 Chain A Binding Site BS02

Receptor Information
>2fl3 Chain A (length=247) Species: 727 (Haemophilus influenzae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNLVELGSKTAKDGFKNEKDIADRFENWKENSEAQDWLVTMGHNLDEIKS
VKAVVLSGYKSDINVQVLVFYKDALDIHNIQVKLVSNKRGFNQIDKHWLA
HYQEMWKFDDNLLRILRHFTGELPPYHSNTKDKRRMFMTEFSQEEQNIVL
NWLEKNRVLVLTDILRGRGDFAAEWVLVAQKVSNNARWILRNINEVLQHY
GSGDISLSPRGSINFGRVTIQRKGGDNGRETANMLQFKIDPTELFDI
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2fl3 DNA nicking by HinP1I endonuclease: bending, base flipping and minor groove expansion.
Resolution2.39 Å
Binding residue
(original residue number in PDB)		L3 V4 G7 S8 A11 F15 F91 R134 S208 R210 Q221 K223 G224 G225 D226 N227 K238
Binding residue
(residue number reindexed from 1)		L3 V4 G7 S8 A11 F15 F91 R134 S208 R210 Q221 K223 G224 G225 D226 N227 K238
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:2fl3, PDBe:2fl3, PDBj:2fl3
PDBsum2fl3
PubMed16473850
UniProtQ5I6E6

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