Structure of PDB 2fiv Chain A Binding Site BS02

Receptor Information
>2fiv Chain A (length=113) Species: 11673 (Feline immunodeficiency virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VGTTTTLEKRPEILIFVNGYPIKFLLNTGADITILNRRDFQVKNSIENGR
QNMIGVGGGKRGTNYINVHLEIRDENYKTQCIFGNVCVLEDNSLIQPLLG
RDNMIKFNIRLVM
Ligand information
Receptor-Ligand Complex Structure
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PDB2fiv Crystal structures of the inactive D30N mutant of feline immunodeficiency virus protease complexed with a substrate and an inhibitor.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		R13 N30 G32 D34 I35 M56 I57 V59 I98 Q99 L101
Binding residue
(residue number reindexed from 1)		R10 N27 G29 D31 I32 M53 I54 V56 I95 Q96 L98
Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
3.4.23.-
3.6.1.23: dUTP diphosphatase.
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:2fiv, PDBe:2fiv, PDBj:2fiv
PDBsum2fiv
PubMed9271500
UniProtP16088|POL_FIVPE Pol polyprotein (Gene Name=pol)

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