Structure of PDB 2ff3 Chain A Binding Site BS02

Receptor Information
>2ff3 Chain A (length=125) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLR
NGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFES
ATFLGYFKSGLKYKKGGVASGFKHV
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2ff3 Chain A Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2ff3 The Structural Basis of Actin Interaction with Multiple WH2/beta-Thymosin Motif-Containing Proteins
Resolution2.0 Å
Binding residue
(original residue number in PDB)		D109 G114 A116
Binding residue
(residue number reindexed from 1)		D82 G87 A89
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0051015 actin filament binding

View graph for
Molecular Function
External links
PDB RCSB:2ff3, PDBe:2ff3, PDBj:2ff3
PDBsum2ff3
PubMed16531231
UniProtP06396|GELS_HUMAN Gelsolin (Gene Name=GSN)

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