Structure of PDB 2fcc Chain A Binding Site BS02

Receptor Information
>2fcc Chain A (length=137) Species: 10665 (Tequatrovirus T4) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TRINLTLVSELADQHLMAEYRELPRVFGAVRKHVANGKRVRDFKISPTFI
LGAGHVTFFYDKLEFLRKRQIELIAECLKRGFNIKDTTVQDISDIPQEFR
GDYIPHEASIAISQARLDEKIAQRPTWYKYYGKAIYA
Ligand information
Receptor-Ligand Complex Structure
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PDB2fcc Structure of T4 Pyrimidine Dimer Glycosylase in a Reduced Imine Covalent Complex with Abasic Site-containing DNA.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		M18 R22 R26 F83 N84 I85 K86 D87
Binding residue
(residue number reindexed from 1)		M17 R21 R25 F82 N83 I84 K85 D86
Enzymatic activity
Catalytic site (original residue number in PDB) T2
Catalytic site (residue number reindexed from 1) T1
Enzyme Commision number 3.2.2.17: deoxyribodipyrimidine endonucleosidase.
4.2.99.18: DNA-(apurinic or apyrimidinic site) lyase.
Gene Ontology
Molecular Function
GO:0000704 pyrimidine dimer DNA N-glycosylase activity
GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0004519 endonuclease activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0016829 lyase activity
GO:0033959 deoxyribodipyrimidine endonucleosidase activity
GO:0140078 class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:2fcc, PDBe:2fcc, PDBj:2fcc
PDBsum2fcc
PubMed16916523
UniProtP04418|END5_BPT4 Endonuclease V

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