Structure of PDB 2ec0 Chain A Binding Site BS02

Receptor Information
>2ec0 Chain A (length=470) Species: 244367 (Foot-and-mouth disease virus C-S8c1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GLIVDTRDVEERVHVMRKTKLAPTVAHGVFNPEFGPAALSNKDPRLNEGV
VLDEVIFSKHKGDTKMSAEDKALFRRCAADYASRLHSVLGTANAPLSIYE
AIKGVDGLDAMEPDTAPGLPWALQGKRRGALIDFENGTVGPEVEAALKLM
EKREYKFACQTFLKDEIRPMEKVRAGKTRIVDVLPVEHILYTRMMIGRFC
AQMHSNNGPQIGSAVGCNPDVDWQRFGTHFAQYRNVWDVDYSAFDANHCS
DAMNIMFEEVFRTEFGFHPNAEWILKTLVNTEHAYENKRITVEGGMPSGC
SATSIINTILNNIYVLYALRRHYEGVELDTYTMISYGDDIVVASDYDLDF
EALKPHFKSLGQTITPADKSDKGFVLGHSITDVTFLKRHFHMDYGTGFYK
PVMASKTLEAILSFARRGTIQEKLISVAGLAVHSGPDEYRRLFEPFQGLF
EIPSYRSLYLRWVNAVCGDA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2ec0 Sequential structures provide insights into the fidelity of RNA replication
Resolution2.75 Å
Binding residue
(original residue number in PDB)		S304 Y336 D338 D339 L386 K387 R388 I411 R416 E422 K423 S426
Binding residue
(residue number reindexed from 1)		S304 Y336 D338 D339 L386 K387 R388 I411 R416 E422 K423 S426
Enzymatic activity
Enzyme Commision number 3.4.22.46: L-peptidase.
3.6.1.15: nucleoside-triphosphate phosphatase.
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003968 RNA-dependent RNA polymerase activity
Biological Process
GO:0006351 DNA-templated transcription
GO:0039694 viral RNA genome replication

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Molecular Function
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Biological Process
External links
PDB RCSB:2ec0, PDBe:2ec0, PDBj:2ec0
PDBsum2ec0
PubMed17517631
UniProtQ9QCE4

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