Structure of PDB 2e9t Chain A Binding Site BS02

Receptor Information
>2e9t Chain A (length=474) Species: 244367 (Foot-and-mouth disease virus C-S8c1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GLIVDTRDVEERVHVMRKTKLAPTVAHGVFNPEFGPAALSNKDPRLNEGV
VLDEVIFSKHKGDTKMSAEDKALFRRCAADYASRLHSVLGTANAPLSIYE
AIKGVDGLDAMEPDTAPGLPWALQGKRRGALIDFENGTVGPEVEAALKLM
EKREYKFACQTFLKDEIRPMEKVRAGKTRIVDVLPVEHILYTRMMIGRFC
AQMHSNNGPQIGSAVGCNPDVDWQRFGTHFAQYRNVWDVDYSAFDANHCS
DAMNIMFEEVFRTEFGFHPNAEWILKTLVNTEHAYENKRITVEGGMPSGC
SATSIINTILNNIYVLYALRRHYEGVELDTYTMISYGDDIVVASDYDLDF
EALKPHFKSLGQTITPADKSDKGFVLGHSITDVTFLKRHFHMDYGTGFYK
PVMASKTLEAILSFARRGTIQEKLISVAGLAVHSGPDEYRRLFEPFQGLF
EIPSYRSLYLRWVNAVCGDAAALE
Ligand information
Receptor-Ligand Complex Structure
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PDB2e9t Sequential structures provide insights into the fidelity of RNA replication
Resolution2.6 Å
Binding residue
(original residue number in PDB)		Y336 D338 D339 L386 K387 I411 R416 T419 E422 K423 S426 L430
Binding residue
(residue number reindexed from 1)		Y336 D338 D339 L386 K387 I411 R416 T419 E422 K423 S426 L430
Enzymatic activity
Enzyme Commision number 3.4.22.46: L-peptidase.
3.6.1.15: nucleoside-triphosphate phosphatase.
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003968 RNA-dependent RNA polymerase activity
Biological Process
GO:0006351 DNA-templated transcription
GO:0039694 viral RNA genome replication

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Molecular Function
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Biological Process
External links
PDB RCSB:2e9t, PDBe:2e9t, PDBj:2e9t
PDBsum2e9t
PubMed17517631
UniProtQ9QCE4

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