Structure of PDB 2e6b Chain A Binding Site BS02

Receptor Information
>2e6b Chain A (length=237) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRILVTNDDGIYSPGLWALAEAASQFGEVFVAAPDTGHAITIAHPVRAYP
HPSPLHAPHFPAYRVRGTPADCVALGLHLFGPVDLVLSGVNLGSNLGHEI
WHSGTVAAAKQGYLFGLSAAAFSVPLNGEVPDFAGLRPWLLRTLETLLRL
ERPFLVNVNLPLRPKGFLWTRQSVRAYEGVVIPGEDPMGRPFYWFAPRPL
KEAEEGTDRWAVAQGFVSATPLRLDLTDETRLQPTLA
Ligand information
Ligand IDWO4
InChIInChI=1S/4O.W/q;;2*-1;
InChIKeyPBYZMCDFOULPGH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[O-][W](=O)(=O)[O-]
ACDLabs 10.04
CACTVS 3.341		[O-][W]([O-])(=O)=O
FormulaO4 W
NameTUNGSTATE(VI)ION
ChEMBL
DrugBank
ZINC
PDB chain2e6b Chain A Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2e6b Crystal Structure of the Stationary Phase Survival Protein SurE with Metal Ion and AMP
Resolution2.5 Å
Binding residue
(original residue number in PDB)		D8 N96 G109 T110
Binding residue
(residue number reindexed from 1)		D8 N91 G104 T105
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.3.5: 5'-nucleotidase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004309 exopolyphosphatase activity
GO:0008252 nucleotidase activity
GO:0008253 5'-nucleotidase activity
GO:0008254 3'-nucleotidase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0106411 XMP 5'-nucleosidase activity
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:2e6b, PDBe:2e6b, PDBj:2e6b
PDBsum2e6b
PubMed17561111
UniProtQ53W92|SURE_THET8 5'-nucleotidase SurE (Gene Name=surE)

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