Structure of PDB 2e5a Chain A Binding Site BS02

Receptor Information
>2e5a Chain A (length=329) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GLILQSISNDVYHNLAVEDWIHDHMNLEGKPVLFLWRNSPTVVIGRHQNP
WQECNLNLMREEGVKLARRRSGGGTVYHDMGNINLTFFTTKKKYDRMENL
KLVVRALKAVHPHLDVQATKRFDLLLDGQFKISGTASKIGRNAAYHHCTL
LCGTDGTFLSSLLKSPYQGIRSNATASTPALVKNLMEKDPTLTCEVVINA
VATEYATSHQIDNHIHLINPTDETVFPGINSKAIELQTWEWIYGKTPKFS
VDTSFTVLHSHVEIKVFIDVKNGRIEVCNIEAPDHWLPLEICDQLNSSLI
GSKFSPIETTVDELHSKWNILCEKIKGIM
Ligand information
Ligand IDPO4
InChIInChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
InChIKeyNBIIXXVUZAFLBC-UHFFFAOYSA-K
SMILES
SoftwareSMILES
CACTVS 3.341[O-][P]([O-])([O-])=O
ACDLabs 10.04[O-]P([O-])([O-])=O
OpenEye OEToolkits 1.5.0[O-]P(=O)([O-])[O-]
FormulaO4 P
NamePHOSPHATE ION
ChEMBL
DrugBankDB14523
ZINC
PDB chain2e5a Chain A Residue 4002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2e5a Crystal structure of bovine Lipoyltransferase in complex with lipoyl-AMP
Resolution2.1 Å
Binding residue
(original residue number in PDB)		K112 H117
Binding residue
(residue number reindexed from 1)		K108 H113
Annotation score1
Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.200: lipoyl amidotransferase.
Gene Ontology
Molecular Function
GO:0016746 acyltransferase activity
GO:0017118 lipoyltransferase activity
Biological Process
GO:0009249 protein lipoylation
GO:0036211 protein modification process
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2e5a, PDBe:2e5a, PDBj:2e5a
PDBsum2e5a
PubMed17570395
UniProtO46419|LIPT_BOVIN Lipoyl amidotransferase LIPT1, mitochondrial (Gene Name=LIPT1)

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