Structure of PDB 2df3 Chain A Binding Site BS02

Receptor Information
>2df3 Chain A (length=114) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KDYSLTMQSSVTVQEGMCVHVRCSFSYPVTDSDPVHGYWFRASWKAPVAT
NNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGRYFFRMEKGNI
KWNYKYDQLSVNVT
Ligand information
Ligand IDCYS
InChIInChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1
InChIKeyXUJNEKJLAYXESH-REOHCLBHSA-N
SMILES
SoftwareSMILES
CACTVS 3.341N[CH](CS)C(O)=O
OpenEye OEToolkits 1.5.0C([C@@H](C(=O)O)N)S
CACTVS 3.341N[C@@H](CS)C(O)=O
ACDLabs 10.04O=C(O)C(N)CS
OpenEye OEToolkits 1.5.0C(C(C(=O)O)N)S
FormulaC3 H7 N O2 S
NameCYSTEINE
ChEMBLCHEMBL863
DrugBankDB00151
ZINCZINC000000895042
PDB chain2df3 Chain A Residue 310 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2df3 The structure of siglec-7 in complex with sialosides: leads for rational structure-based inhibitor design
Resolution1.9 Å
Binding residue
(original residue number in PDB)		C41 V42 H43
Binding residue
(residue number reindexed from 1)		C18 V19 H20
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2df3, PDBe:2df3, PDBj:2df3
PDBsum2df3
PubMed16623661
UniProtQ9Y286|SIGL7_HUMAN Sialic acid-binding Ig-like lectin 7 (Gene Name=SIGLEC7)

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