Structure of PDB 2bz0 Chain A Binding Site BS02

Receptor Information
>2bz0 Chain A (length=168) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MQLKRVAEAKLPTPWGDFLMVGFEELATGHDHVALVYGDISGHTPVLARV
HSECLTGDALFSLRCDCGFQLEAALTQIAEEGRGILLYHRQEGRNIGLLN
KIRAYALQDQGYDTVEGFAADERDFTLCADMFKLLGVNEVRLLTNNPKKV
EILTEAGINIVERVPLIV
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain2bz0 Chain A Residue 1175 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2bz0 GTP Cyclohydrolase II Structure and Mechanism.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		H51 S52
Binding residue
(residue number reindexed from 1)		H51 S52
Annotation score1
Enzymatic activity
Enzyme Commision number 3.5.4.25: GTP cyclohydrolase II.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003824 catalytic activity
GO:0003935 GTP cyclohydrolase II activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0009231 riboflavin biosynthetic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2bz0, PDBe:2bz0, PDBj:2bz0
PDBsum2bz0
PubMed16115872
UniProtP0A7I7|RIBA_ECOLI GTP cyclohydrolase-2 (Gene Name=ribA)

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