Structure of PDB 2aq4 Chain A Binding Site BS02

Receptor Information
>2aq4 Chain A (length=428) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KRIVACDDPDFLTSYFAHSRLHHLSAWKANLKDKFLNENIHKYTKITDKD
TYIIFHIDFDCFFATVAYLCRSSSFSACDFKRDPIVVCHGTKNSDIASCN
YVARSYGIKNGMWVSQAEKMLPNGIKLISLPYTFEQFQLKSEAFYSTLKR
LNIFNLILPISIDEAVCVRIIPDTLNARLCEEIRQEIFQGTNGCTVSIGC
SDSLVLARLALKMAKPNGYNITFKSNLSEEFWSSFKLDDLPGVGHSTLSR
LESTFDSPHSLNDLRKRYTLDALKASVGSKLGMKIHLALQGQDDEESLKI
LYDPKEVLQRKSLSIDINWGIRFKNITQVDLFIERGCQYLLEKLNEINKT
TSQITLKLMRRCKDAPIEPPKYMGMGRCDSFSRSSRLGIPTNEFGIIATE
MKSLYRTLGCPPMELRGLALQFNKLVDV
Ligand information
Receptor-Ligand Complex Structure
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PDB2aq4 Rev1 employs a novel mechanism of DNA synthesis using a protein template.
Resolution2.32 Å
Binding residue
(original residue number in PDB)		I307 Y319 F320 H322 S323 R324 L325 H326 S329 K336 H393 G394 T395 K396 N397 S398 D399 S589 K590 E606 R620 K621 L623 S624 I625 D626 N628 W629 K681 Y682 G684 M685 G686
Binding residue
(residue number reindexed from 1)		I3 Y15 F16 H18 S19 R20 L21 H22 S25 K32 H89 G90 T91 K92 N93 S94 D95 S279 K280 E296 R310 K311 L313 S314 I315 D316 N318 W319 K371 Y372 G374 M375 G376
Enzymatic activity
Enzyme Commision number 2.7.7.-
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:2aq4, PDBe:2aq4, PDBj:2aq4
PDBsum2aq4
PubMed16195463
UniProtP12689|REV1_YEAST DNA repair protein REV1 (Gene Name=REV1)

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