Structure of PDB 2aps Chain A Binding Site BS02

Receptor Information

>2aps Chain A (length=155) Species: 715 (Actinobacillus pleuropneumoniae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

EKLVVQVQQLDPVKGNKDVGTVEITESAYGLVFTPHLHGLAQGLHGFHIH
QNPSCEPKEKDGKLVAGLGAGGHWDPKETKQHGYPWSDNAHLGDLPALFV
EHDGSATNPVLAPRLKKLDEVKGHSLMIHEGGDNHSDHPAPLGGGGPRMA
CGVIK

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

2aps Chain A Residue 400 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	2aps Cu,Zn superoxide dismutase structure from a microbial pathogen establishes a class with a conserved dimer interface.
Resolution	1.9 Å
Binding residue (original residue number in PDB)	H85 H94 H103 D106
Binding residue (residue number reindexed from 1)	H73 H82 H91 D94
Annotation score	1

Enzymatic activity

Enzyme Commision number

1.15.1.1: superoxide dismutase.

Gene Ontology

	Molecular Function
GO:0004784	superoxide dismutase activity
GO:0005507	copper ion binding
GO:0016209	antioxidant activity
GO:0016491	oxidoreductase activity
GO:0046872	metal ion binding

	Biological Process
GO:0006801	superoxide metabolic process
GO:0019430	removal of superoxide radicals
GO:0098869	cellular oxidant detoxification

	Cellular Component
GO:0042597	periplasmic space

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Cellular Component

External links

PDB	RCSB:2aps, PDBe:2aps, PDBj:2aps
PDBsum	2aps
PubMed	10656823
UniProt	P24702\|SODC_ACTPL Superoxide dismutase [Cu-Zn] (Gene Name=sodC)

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