Structure of PDB 1yty Chain A Binding Site BS02

Receptor Information
>1yty Chain A (length=184) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLEIMIKF
NRLNRLTTDFNVIVEALSKSKAELMEISEDKTKIRRSPSKPLPEVTDEYK
NDVKNRSVYIKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLHKAFKGSIF
VVFDSIESAKKFVETPGQKYKETDLLILFKDDYF
Ligand information
Receptor-Ligand Complex Structure
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PDB1yty Structural Basis for Recognition and Sequestration of UUU(OH) 3' Temini of Nascent RNA Polymerase III Transcripts by La, a Rheumatic Disease Autoantigen.
Resolution2.29 Å
Binding residue
(original residue number in PDB)
Q20 Y23 Y24 D33 F35 F55 N56 R57 L124 I140
Binding residue
(residue number reindexed from 1)
Q15 Y18 Y19 D28 F30 F50 N51 R52 L119 I135
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
Biological Process
GO:0006396 RNA processing
Cellular Component
GO:0005634 nucleus
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:1yty, PDBe:1yty, PDBj:1yty
PDBsum1yty
PubMed16387655
UniProtP05455|LA_HUMAN Lupus La protein (Gene Name=SSB)

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