Structure of PDB 1yew Chain A Binding Site BS02

Receptor Information

>1yew Chain A (length=382) Species: 243233 (Methylococcus capsulatus str. Bath) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

HGEKSQAAFMRMRTIHWYDLSWSKEKVKINETVEIKGKFHVFEGWPETVD
EPDVAFLNVGMPGPVFIRKESYIGGQLVPRSVRLEIGKTYDFRVVLKARR
PGDWHVHTMMNVQGGGPIIGPGKWITVEGSMSEFRNPVTTLTGQTVDLEN
YNEGNTYFWHAFWFAIGVAWIGYWSRRPIFIPRLLMVDAGRADELVSATD
RKVAMGFLAATILIVVMAMSSANSKYPITIPLQAGTMRGMKPLELPAPTV
SVKVEDATYRVPGRAMRMKLTITNHGNSPIRLGEFYTASVRFLDSDVYKD
TTGYPEDLLAEDGLSVSDNSPLAPGETRTVDVTASDAAWEVYRLSDIIYD
PDSRFAGLLFFFDATGNRQVVQIDAPLIPSFM

Ligand information

InChI=1S/2Cu

ALKZAGKDWUSJED-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 CACTVS 3.341 OpenEye OEToolkits 1.5.0	[Cu][Cu]

Formula

Cu2

Name

DINUCLEAR COPPER ION

ChEMBL

DrugBank

ZINC

PDB chain

1yew Chain A Residue 3 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1yew Crystal structure of a membrane-bound metalloenzyme that catalyses the biological oxidation of methane.
Resolution	2.801 Å
Binding residue (original residue number in PDB)	H33 H137 H139
Binding residue (residue number reindexed from 1)	H1 H105 H107
Annotation score	1

Enzymatic activity

Enzyme Commision number

1.14.18.3: methane monooxygenase (particulate).

Gene Ontology

	Molecular Function
GO:0004497	monooxygenase activity
GO:0046872	metal ion binding

	Cellular Component
GO:0016020	membrane

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Molecular Function

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Cellular Component

External links

PDB	RCSB:1yew, PDBe:1yew, PDBj:1yew
PDBsum	1yew
PubMed	15674245
UniProt	G1UBD1\|PMOB_METCA Particulate methane monooxygenase alpha subunit (Gene Name=pmoB1)

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