Structure of PDB 1y6f Chain A Binding Site BS02

Receptor Information
>1y6f Chain A (length=394) Species: 10665 (Tequatrovirus T4) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MGSMRICIFMARGLEGCGVTKFSLEQRDWFIKNGHEVTLVYAKDKSFTRT
SSHDHKSFSIPVILAKEYDKALKLVNDCDILIINSVPATSVQEATINNYK
KLLDNIKPSIRVVVYQHDHSVLSLRRNLGLEETVRRADVIFSHSDNGDFN
KVLMKEWYPEEAPTVYNFQPPMDIVKVRSTYWKDVSEINMNINRWIGRTT
TWKGFYQMFDFHEKFLKPAGKSTVMEGLERSPAFIAIKEKGIPYEYYGNR
EIDKMNLAPNQPAQILDCYINSEMLERMSKSGFGYQLSKLNQKYLQRSLE
YTHLELGACGTIPVFWKSTGENLKFRVDNTPLTSHDSGIIWFDENDMEST
FERIKELSSDRALYDREREKAYEFLYQHQDSSFCFKEQFDIITK
Ligand information
Receptor-Ligand Complex Structure
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PDB1y6f Structural evidence of a passive base-flipping mechanism for AGT, an unusual GT-B glycosyltransferase.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		R1122 R1236 S1237 P1238 I1241 R1256
Binding residue
(residue number reindexed from 1)		R125 R230 S231 P232 I235 R250
Enzymatic activity
Enzyme Commision number 2.4.1.26: DNA alpha-glucosyltransferase.
Gene Ontology
Molecular Function
GO:0016757 glycosyltransferase activity
GO:0033820 DNA alpha-glucosyltransferase activity
Biological Process
GO:0006304 DNA modification
GO:0019049 virus-mediated perturbation of host defense response
GO:0039504 symbiont-mediated suppression of host adaptive immune response
GO:0098672 symbiont-mediated suppression of host CRISPR-cas system
GO:0099018 symbiont-mediated evasion of host restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:1y6f, PDBe:1y6f, PDBj:1y6f
PDBsum1y6f
PubMed16081100
UniProtP04519|GSTA_BPT4 DNA alpha-glucosyltransferase (Gene Name=agt)

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