Structure of PDB 1y0y Chain A Binding Site BS02

Receptor Information
>1y0y Chain A (length=335) Species: 53953 (Pyrococcus horikoshii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MVDYELLKKVVEAPGVSGYEFLGIRDVVIEEIKDYVDEVKVDKLGNVIAH
KKGEGPKVMIAAHMDQIGLMVTHIEKNGFLRVAPIGGVDPKTLIAQRFKV
WIDKGKFIYGVGASAPDWDQIFIDIGAESKEEAEDMGVKIGTVITWDGRL
ERLGKHRFVSIAFDDRIAVYTILEVAKQLKDAKADVYFVATVQEEVGLRG
ARTSAFGIEPDYGFAIDVTIAADIPGTPEHKQVTHLGKGTAIKIMDRSVI
CHPTIVRWLEELAKKHEIPYQLEILLGGGTDAGAIHLTKAGVPTGALSVP
ARYIHSNTEVVDERDVDATVELMTKALENIHELKI
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1y0y Chain A Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1y0y Crystal Structure of TET Protease Reveals Complementary Protein Degradation Pathways in Prokaryotes
Resolution1.6 Å
Binding residue
(original residue number in PDB)		H68 D182 D235
Binding residue
(residue number reindexed from 1)		H63 D164 D217
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.11.-
Gene Ontology
Molecular Function
GO:0004177 aminopeptidase activity
GO:0008237 metallopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1y0y, PDBe:1y0y, PDBj:1y0y
PDBsum1y0y
PubMed15713475
UniProtO59196|TET_PYRHO Tetrahedral aminopeptidase (Gene Name=frvX)

[Back to BioLiP]