Structure of PDB 1y02 Chain A Binding Site BS02

Receptor Information
>1y02 Chain A (length=91) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PSCKSCGAHFANTARKQTCLDCKKNFCMTCSSQPRLCLLCQRFRATAFQR
EELMKMKVKDLRDYLSLHDISTEMCREKEELVLLVLGQQPV
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1y02 Chain A Residue 162 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1y02 Crystal structure of a FYVE-type zinc finger domain from the caspase regulator CARP2.
Resolution1.8 Å
Binding residue
(original residue number in PDB)
C22 C25 C46 C49
Binding residue
(residue number reindexed from 1)
C3 C6 C27 C30
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
External links
PDB RCSB:1y02, PDBe:1y02, PDBj:1y02
PDBsum1y02
PubMed15576038
UniProtQ8WZ73|RFFL_HUMAN E3 ubiquitin-protein ligase rififylin (Gene Name=RFFL)

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