Structure of PDB 1xns Chain A Binding Site BS02

Receptor Information
>1xns Chain A (length=322) Species: 10678 (Punavirus P1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDEVRKNLMDMFRDRQAFSEHTWKMLLSVCRSWAAWCKLNNRKWFPAEPE
DVRDYLLYLQARGLAVKTIQQHLGQLNMLHRRSGLPRPSDSNAVSLVMRR
IRKENVDAGERAKQALAFERTDFDQVRSLMENSDRCQDIRNLAFLGIAYN
TLLRIAEIARIRVKDISRTDGGRMLIHIGRTKTLVSTAGVEKALSLGVTK
LVERWISVSGVADDPNNYLFCRVRKNGVAAPSATSQLSTRALEGIFEATH
RLIYGAKDDSGQRYLAWSGHSARVGAARDMARAGVSIPEIMQAGGWTNVN
IVMNYIRNLDSETGAMVRLLED
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1xns Peptide trapping of the Holliday junction intermediate in Cre-loxP site-specific recombination.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		K43 M44 S47 R50 R81 A84 K86 T87 Q90 K132 R159 R173 T202 R241 V242 R243 K244 L256 S257 R259 R282 W315 Y324
Binding residue
(residue number reindexed from 1)		K24 M25 S28 R31 R62 A65 K67 T68 Q71 K113 R140 R154 T183 R222 V223 R224 K225 L237 S238 R240 R263 W296 Y305
Binding affinityPDBbind-CN: Kd=1.3uM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006310 DNA recombination
GO:0015074 DNA integration

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1xns, PDBe:1xns, PDBj:1xns
PDBsum1xns
PubMed15591069
UniProtP06956|RECR_BPP1 Recombinase cre (Gene Name=cre)

[Back to BioLiP]