Structure of PDB 1x8o Chain A Binding Site BS02

Receptor Information
>1x8o Chain A (length=184) Species: 13249 (Rhodnius prolixus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ACTKNAIAQTGFNKDKYFNGDVWYVTDYLDLEPDDVPKRYCAALAAGTAS
GKLKEALYHYDPKTQDTFYDVSELQVESLGKYTANFKKVDKNGNVKVAVT
AGNYYTFTVMYADDSSALIHTCLHKGNKDLGDLYAVLNRNKDAAAGDKVK
SAVSAATLEFSKFISTKENNCAYDNDSLKSLLTK
Ligand information
Ligand IDNO
InChIInChI=1S/HNO/c1-2/h1H
InChIKeyODUCDPQEXGNKDN-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.385
OpenEye OEToolkits 2.0.7		[N]=O
FormulaN O
NameNITRIC OXIDE;
Nitrogen monoxide
ChEMBLCHEMBL1234765
DrugBank
ZINC
PDB chain1x8o Chain A Residue 203 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1x8o Protein functional cycle viewed at atomic resolution: conformational change and mobility in nitrophorin 4 as a function of pH and NO binding
Resolution1.01 Å
Binding residue
(original residue number in PDB)		L130 L133
Binding residue
(residue number reindexed from 1)		L130 L133
Annotation score1
Enzymatic activity
Enzyme Commision number 1.7.6.1: nitrite dismutase.
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0051381 histamine binding
GO:0070026 nitric oxide binding
Biological Process
GO:0042311 vasodilation
Cellular Component
GO:0005576 extracellular region

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Cellular Component
External links
PDB RCSB:1x8o, PDBe:1x8o, PDBj:1x8o
PDBsum1x8o
PubMed15504026
UniProtQ94734|NP4_RHOPR Nitrophorin-4

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