Structure of PDB 1wep Chain A Binding Site BS02

Receptor Information
>1wep Chain A (length=79) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSSGSSGMALVPVYCLCRQPYNVNHFMIECGLCQDWFHGSCVGIEEENAV
DIDIYHCPDCEAVFGPSIMKNWHSGPSSG
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1wep Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1wep Solution structure of PHD domain in protein AA017385
ResolutionN/A
Binding residue
(original residue number in PDB)		C30 C33 C57 C60
Binding residue
(residue number reindexed from 1)		C30 C33 C57 C60
Annotation score1
Enzymatic activity
Enzyme Commision number 1.14.11.27: [histone H3]-dimethyl-L-lysine(36) demethylase.
1.14.11.65: [histone H3]-dimethyl-L-lysine(9) demethylase.
Gene Ontology
Cellular Component
GO:0048188 Set1C/COMPASS complex

View graph for
Cellular Component
External links
PDB RCSB:1wep, PDBe:1wep, PDBj:1wep
PDBsum1wep
PubMed
UniProtQ80TJ7|PHF8_MOUSE Histone lysine demethylase PHF8 (Gene Name=Phf8)

[Back to BioLiP]