Structure of PDB 1wcf Chain A Binding Site BS02

Receptor Information

>1wcf Chain A (length=162) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

HMQFDVTIEIPKGQRNKYEVDHETGRVRLDRYLYTPMAYPTDYGFIEDTL
GDDGDPLDALVLLPQPVFPGVLVAARPVGMFRMVDEHGGDDKVLCVPAGD
PRWDHVQDIGDVPAFELDAIKHFFVHYKDLEPGKFVKAADWVDRAEAEAE
VQRSVERFKAGT

Ligand information

Ligand ID

InChI

InChI=1S/K/q+1

InChIKey

NPYPAHLBTDXSSS-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 CACTVS 3.341 OpenEye OEToolkits 1.5.0	[K+]

Formula

Name

POTASSIUM ION

PDB chain

1wcf Chain A Residue 1163 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	1wcf Structure of the Mycobacterium Tuberculosis Soluble Inorganic Pyrophosphatase Rv3628 at Ph 7.0.
Resolution	1.54 Å
Binding residue (original residue number in PDB)	D52 P55 D57 D89
Binding residue (residue number reindexed from 1)	D53 P56 D58 D90
Annotation score	1

Enzymatic activity

Enzyme Commision number

3.6.1.1: inorganic diphosphatase.

Gene Ontology

	Molecular Function
GO:0000287	magnesium ion binding
GO:0004427	inorganic diphosphate phosphatase activity
GO:0016787	hydrolase activity
GO:0046872	metal ion binding

	Biological Process
GO:0006796	phosphate-containing compound metabolic process

	Cellular Component
GO:0005576	extracellular region
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0044228	host cell surface

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:1wcf, PDBe:1wcf, PDBj:1wcf
PDBsum	1wcf
PubMed	21821883
UniProt	P9WI55\|IPYR_MYCTU Inorganic pyrophosphatase (Gene Name=ppa)

[Back to BioLiP]