Structure of PDB 1w0u Chain A Binding Site BS02

Receptor Information
>1w0u Chain A (length=55) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KKQKWTVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKDRWRTMK
RLGMN
Ligand information
Receptor-Ligand Complex Structure
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PDB1w0u How the Human Telomeric Proteins Trf1 and Trf2 Recognize Telomeric DNA: A View from High-Resolution Crystal Structures
Resolution1.8 Å
Binding residue
(original residue number in PDB)		K447 Q448 K449 W450 R482 M486 D489 R490 T493
Binding residue
(residue number reindexed from 1)		K2 Q3 K4 W5 R37 M41 D44 R45 T48
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0042162 telomeric DNA binding
Biological Process
GO:0000723 telomere maintenance
GO:0031848 protection from non-homologous end joining at telomere
Cellular Component
GO:0000781 chromosome, telomeric region
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1w0u, PDBe:1w0u, PDBj:1w0u
PDBsum1w0u
PubMed15608617
UniProtQ15554|TERF2_HUMAN Telomeric repeat-binding factor 2 (Gene Name=TERF2)

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