Structure of PDB 1vq8 Chain A Binding Site BS02

Receptor Information

>1vq8 Chain A (length=237) Species: 2238 (Haloarcula marismortui)

GRRIQGQRRGRGTSTFRAPSHRYKADLEHRKVEDGDVIAGTVVDIEHDPA
RSAPVAAVEFEDGDRRLILAPEGVGVGDELQVGVSAEIAPGNTLPLAEIP
EGVPVCNVESSPGDGGKFARASGVNAQLLTHDRNVAVVKLPSGEMKRLDP
QCRATIGVVAGGGRTDKPFVKAGNKHHKMKARGTKWPNVRGVAMNAVDHP
FGGGGRQHPGKPKSISRNAPPGRKVGDIASKRTGRGG

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 1vq8 Chain A Residue 8066

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1vq8 Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
• Resolution: 2.2 Å
• Binding residue (original residue number in PDB): D26 L27 R120
• Binding residue (residue number reindexed from 1): D26 L27 R120
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0015934 large ribosomal subunit
• GO:0022625 cytosolic large ribosomal subunit
• GO:0022626 cytosolic ribosome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:1vq8, PDBe:1vq8, PDBj:1vq8
• PDBsum: 1vq8
• PubMed: 16285925
• UniProt: P20276|RL2_HALMA Large ribosomal subunit protein uL2 (Gene Name=rpl2)