Structure of PDB 1tbo Chain A Binding Site BS02

Receptor Information
>1tbo Chain A (length=66) Species: 10117 (Rattus rattus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QTDDPRNKHKFRLHSYSSPTFCDHCGSLLYGLVHQGMKCSCCEMNVHRRC
VRSVPSLCGVDHTERR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1tbo Chain A Residue 2 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1tbo NMR structure of a protein kinase C-gamma phorbol-binding domain and study of protein-lipid micelle interactions.
ResolutionN/A
Binding residue
(original residue number in PDB)		C115 C118 H140 C143
Binding residue
(residue number reindexed from 1)		C22 C25 H47 C50
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.11.13: protein kinase C.
External links
PDB RCSB:1tbo, PDBe:1tbo, PDBj:1tbo
PDBsum1tbo
PubMed9271501
UniProtP63319|KPCG_RAT Protein kinase C gamma type (Gene Name=Prkcg)

[Back to BioLiP]