Structure of PDB 1t7p Chain A Binding Site BS02

Receptor Information
>1t7p Chain A (length=662) Species: 10760 (Escherichia phage T7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIVSDIEANALLESVTKFHCGVIYDYSTAEYVSYRPSDFGAYLDALEAEV
ARGGLIVFHNGHKYDVPALTKLAKLQLNREFHLPRENCIDTLVLSRLIHS
NLKDTDMGLLRSGKLPGALEAWGYRLGEMKGEYKDDFKRMLEEQGEEYVD
GMEWWNFNEEMMDYNVQDVVVTKALLEKLLSDKHYFPPEIDFTDVGYTTF
WSESLEAVDIEHRAAWLLAKQERNGFPFDTKAIEELYVELAARRSELLRK
LTETFGSWYQPKGGTEMFCHPRTGKPLPKYPRIKTPKEYVAGAPYTPVEH
VVFNPSSRDHIQKKLQEAGWVPTKYTDKGAPVVDDEVLEGVRVDDPEKQA
AIDLIKEYLMIQKRIGQSAEGDKAWLRYVAEDGKIHGSVNPNGAVTGRAT
HAFPNLAQIPGVRSPYGEQCRAAFGAEHHLDGITGKPWVQAGIDASGLEL
RCLAHFMARFDNGEYAHEILNGDIHTKNQIAAELPTRDNAKTFIYGFLYG
AGDEKIGQIVGAGKERGKELKKKFLENTPAIAALRESIQQTLVEKWKRRW
IKGLDGRKVHVRSPHAALNTLLQSAGALICKLWIIKTEEMLVEKGLKHGW
DGDFAYMAWVHDEIQVGCRTEEIAQVVIETAQEAMRWVGDHWNFRCLLDT
EGKMGPNWAICH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1t7p Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 A resolution.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		S337 S338 K404 A425 V426 T431 H432 A433 N436 Q439 G527 Y530 A532 G533 K536 R604 H607 N611 Q615
Binding residue
(residue number reindexed from 1)		S306 S307 K373 A394 V395 T400 H401 A402 N405 Q408 G496 Y499 A501 G502 K505 R562 H565 N569 Q573
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
3.1.11.-
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0004527 exonuclease activity
GO:0004529 DNA exonuclease activity
GO:0005515 protein binding
GO:0008408 3'-5' exonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006302 double-strand break repair
GO:0039693 viral DNA genome replication
GO:0090592 DNA synthesis involved in DNA replication

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Molecular Function
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Biological Process
External links
PDB RCSB:1t7p, PDBe:1t7p, PDBj:1t7p
PDBsum1t7p
PubMed9440688
UniProtP00581|DPOL_BPT7 DNA-directed DNA polymerase (Gene Name=5)

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