Structure of PDB 1t16 Chain A Binding Site BS02

Receptor Information

>1t16 Chain A (length=427) Species: 562 (Escherichia coli)

AGFQLNEFSSSGLGRAYSGEGAIADDAGNVSRNPALITMFDRPTFSAGAV
YIDPDVNISGTSPSGRSLKADNIAPTAWVPNMHFVAPINDQFGWGASITS
NYGLATEFNDTYAGGSVGGTTDLETMNLNLSGAYRLNNAWSFGLGFNAVY
ARAKIERFAGDLGQLVAGQIMQSPAGQTQQGQALAATANGIDSNTKIAHL
NGNQWGFGWNAGILYELDKNNRYALTYRSEVKIDFKGNYSSDLNRAFNNY
GLPIPTATGGATQSGYLTLNLPEMWEVSGYNRVDPQWAIHYSLAYTSWSQ
FQQLKATSTSGDTLFQKHEGFKDAYRIALGTTYYYDDNWTFRTGIAFDDS
PVPAQNRSISIPDQDRFWLSAGTTYAFNKDASVDVGVSYMHGQSVKINEG
PYQFESEGKAWLFGTNFNYAFHHHHHH

Ligand information

• Ligand ID: CU
• InChI: InChI=1S/Cu/q+2
• InChIKey: JPVYNHNXODAKFH-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Cu+2]
  CACTVS 3.341: [Cu++]
• Formula: Cu
• Name: COPPER (II) ION
• DrugBank: DB14552
• PDB chain: 1t16 Chain A Residue 429

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1t16 Crystal structure of the long-chain fatty acid transporter FadL.
• Resolution: 2.6 Å
• Binding residue (original residue number in PDB): H422 H424
• Binding residue (residue number reindexed from 1): H422 H424
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:0015483 long-chain fatty acid transporting porin activity
• GO:0022834 ligand-gated channel activity

Biological Process

• GO:0006869 lipid transport
• GO:0015909 long-chain fatty acid transport
• GO:0055085 transmembrane transport

Cellular Component

• GO:0009279 cell outer membrane

External links

• PDB: RCSB:1t16, PDBe:1t16, PDBj:1t16
• PDBsum: 1t16
• PubMed: 15178802
• UniProt: P10384|FADL_ECOLI Long-chain fatty acid transport protein (Gene Name=fadL)