Structure of PDB 1szb Chain A Binding Site BS02

Receptor Information
>1szb Chain A (length=167) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDL
ELSHLCEYDFVKLSSGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDIT
FRSDYSNEKPFTGFEAFYAAEDIDECQVAPGEAPTCDHHCHNHLGGFYCS
CRAGYVLHRNKRTCSEQ
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1szb Chain A Residue 1003 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1szb The X-ray structure of human MBL-associated protein 19 (MAp19) and its interaction site with mannan-binding lectin and L-ficolin
Resolution2.5 Å
Binding residue
(original residue number in PDB)		E52 D60 D105 S107 N108
Binding residue
(residue number reindexed from 1)		E51 D59 D104 S106 N107
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.21.104: mannan-binding lectin-associated serine protease-2.
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:1szb, PDBe:1szb, PDBj:1szb
PDBsum1szb
PubMed15117939
UniProtO00187|MASP2_HUMAN Mannan-binding lectin serine protease 2 (Gene Name=MASP2)

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