Structure of PDB 1sq3 Chain A Binding Site BS02

Receptor Information
>1sq3 Chain A (length=162) Species: 224325 (Archaeoglobus fulgidus DSM 4304) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SISEKMVEALNRQINAEIYSAYLYLSMASYFDSIGLKGFSNWMRVQWQEE
LMHAMKMFDFVSERGGRVKLYAVEEPPSEWDSPLAAFEHVYEHEVNVTKR
IHELVEMAMQEKDFATYNFLQWYVAEQVEEEASALDIVEKLRLIGEDKRA
LLFLDKELSLRQ
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain1sq3 Chain A Residue 902 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1sq3 Crystal structures of a tetrahedral open pore ferritin from the hyperthermophilic archaeon Archaeoglobus fulgidus.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		E52 E96 E132
Binding residue
(residue number reindexed from 1)		E50 E94 E130
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004322 ferroxidase activity
GO:0008198 ferrous iron binding
GO:0008199 ferric iron binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006826 iron ion transport
GO:0006879 intracellular iron ion homeostasis
GO:0006880 intracellular sequestering of iron ion
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Biological Process
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Cellular Component
External links
PDB RCSB:1sq3, PDBe:1sq3, PDBj:1sq3
PDBsum1sq3
PubMed15837202
UniProtO29424

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