Structure of PDB 1skm Chain A Binding Site BS02

Receptor Information
>1skm Chain A (length=327) Species: 726 (Haemophilus haemolyticus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIEIKDKQLTGLRFIDLFAGLGGFRLALESCGAECVYSNEWDKYAQEVYE
MNFGEKPEGDITQVNEKTIPDHDILCAGFPCQAFSISGKQKGFEDSRGTL
FFDIARIVREKKPKVVFMENVKNFASHDNGNTLEVVKNTMNELDYSFHAK
VLNALDYGIPQKRERIYMICFRNDLNIQNFQFPKPFELNTFVKDLLLPDS
EVEHLVIDRKDLVMTNQEIEQTTPKTVRLGIVGKGGQGERIYSTRGIAIT
LSAYGGGIFAKTGGYLVNGKTRKLHPRECARVMGYPDSYKVHPSTSQAYK
QFGNSVVINVLQYIAYNIGSSLNFKPY
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1skm Caught in the act: visualization of an intermediate in the DNA base-flipping pathway induced by HhaI methyltransferase
Resolution2.2 Å
Binding residue
(original residue number in PDB)		S85 I86 S87 G88 K89 R97 K162 T226 R228 Q237 R240 Y242 T250 S252 Y254 G255
Binding residue
(residue number reindexed from 1)		S85 I86 S87 G88 K89 R97 K162 T226 R228 Q237 R240 Y242 T250 S252 Y254 G255
Enzymatic activity
Catalytic site (original residue number in PDB) C81 E119 R163 R165
Catalytic site (residue number reindexed from 1) C81 E119 R163 R165
Enzyme Commision number 2.1.1.37: DNA (cytosine-5-)-methyltransferase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003886 DNA (cytosine-5-)-methyltransferase activity
GO:0008168 methyltransferase activity
Biological Process
GO:0009307 DNA restriction-modification system
GO:0032259 methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:1skm, PDBe:1skm, PDBj:1skm
PDBsum1skm
PubMed15273274
UniProtP05102|MTH1_HAEPH Type II methyltransferase M.HhaI (Gene Name=hhaIM)

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