Structure of PDB 1se0 Chain A Binding Site BS02

Receptor Information
>1se0 Chain A (length=97) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NDLNREETRLKTFTDWPLDWLDKRQLAQTGMYFTHAGDKVKCFFCGVEIG
SWEQEDQPVPEHQRWSPNCPLLRRRTTNNVPINAEALDRILPPISYD
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1se0 Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1se0 Molecular mechanisms of DrICE inhibition by DIAP1 and removal of inhibition by Reaper, Hid and Grim.
Resolution1.75 Å
Binding residue
(original residue number in PDB)		C80 C83 H100 C107
Binding residue
(residue number reindexed from 1)		C42 C45 H62 C69
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
External links
PDB RCSB:1se0, PDBe:1se0, PDBj:1se0
PDBsum1se0
PubMed15107838
UniProtQ24306|DIAP1_DROME Death-associated inhibitor of apoptosis 1 (Gene Name=Diap1)

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