Structure of PDB 1s0v Chain A Binding Site BS02

Receptor Information
>1s0v Chain A (length=857) Species: 10760 (Escherichia phage T7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NTINIAKNDFSDIELAAIPFNTLADHYGERLAREQLALEHESYEMGEARF
RKMFERQLKAGEVADNAAAKPLITTLLPKMIARINDWFEEVKAKRGKRPT
AFQFLQEIKPEAVAYITIKTTLACLTSADNTTVQAVASAIGRAIEDEARF
GRIRDLEAKHFKKNVEEQLNKRVGHVYKKAFMQVVEADMLSKGLLGGEAW
SSWHKEDSIHVGVRCIEMLIESTGMVSLHRQNAGVVGQDSETIELAPEYA
EAIATRAGALAGISPMFQPCVVPPKPWTGITGGGYWANGRRPLALVRTHS
KKALMRYEDVYMPEVYKAINIAQNTAWKINKKVLAVANVITKWKHCPVED
IPAIEALTAWKRAAAAVYRKDKARKSRRISLEFMLEQANKFANHKAIWFP
YNMDWRGRVYAVSMFNPQGNDMTKGLLTLAKGKPIGKEGYYWLKIHGANC
AGVDKVPFPERIKFIEENHENIMACAKSPLENTWWAEQDSPFCFLAFCFE
YAGVQHHGLSYNCSLPLAFDGSCSGIQHFSAMLRDEVGGRAVNLLPSETV
QDIYGIVAKKVNEILQADAINGTDNEVVTVTDENTGEISEKVKLGTKALA
GQWLAYGVTRSVTKRSVMTLAYGSKEFGFRQQVLEDTIQPAIDSGKGLMF
TQPNQAAGYMAKLIWESVSVTVVAAVEAMNWLKSAAKLLAAEVKDKKTGE
ILRKRCAVHWVTPDGFPVWQEYKKPIQTRLNLMFLGQFRDSEIDAHKQES
GIAPNFVHSQDGSHLRKTVVWAHEKYGIESFALIHDSFGTIPADAANLFK
AVRETMVDTYESCDVLADFYDQFADQLHESQLDKMPALPAKGNLNLRDIL
ESDFAFA
Ligand information
Receptor-Ligand Complex Structure
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PDB1s0v Structural basis for substrate selection by t7 RNA polymerase.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		K172 R386 K389 S393 R394 G436 N437 I810 D812
Binding residue
(residue number reindexed from 1)		K171 R369 K372 S376 R377 G419 N420 I784 D786
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
Biological Process
GO:0006351 DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1s0v, PDBe:1s0v, PDBj:1s0v
PDBsum1s0v
PubMed15016373
UniProtP00573|RPOL_BPT7 T7 RNA polymerase (Gene Name=1)

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