Structure of PDB 1r1z Chain A Binding Site BS02

Receptor Information
>1r1z Chain A (length=247) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HHHHSSGLVPRGSHMAGTQAHRRFEYKYSFKGPHLVQSDGTVPFWAHAGN
AIPSADQIRIAPSLKSQRGSVWTKTKAAFENWEVEVTFRVTGRGRIGADG
LAIWYTENQGLDGPVFGSADMWNGVGIFFDSFDNDGKKNNPAIVVVGNNG
QINYDHQNDGATQALASCQRDFRNKPYPVRAKITYYQKTLTVMINNGFTP
DKNDYEFCAKVENMVIPTQGHFGISAATGGLADDHDVLSFLTFQLTE
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1r1z Chain A Residue 286 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1r1z The Crystal Structure of the Carbohydrate-recognition Domain of the Glycoprotein Sorting Receptor p58/ERGIC-53 Reveals an Unpredicted Metal-binding Site and Conformational Changes Associated with Calcium Ion Binding.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		D163 D165 N169 N170 D189
Binding residue
(residue number reindexed from 1)		D133 D135 N139 N140 D159
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:1r1z, PDBe:1r1z, PDBj:1r1z
PDBsum1r1z
PubMed14643651
UniProtQ62902|LMAN1_RAT Protein ERGIC-53 (Gene Name=Lman1)

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